A computer simulation using the GEANT4 nuclear transport toolkit was developed to model the production of isotopes from rare isotope beam targets used at ISAC. In combination with in-depth isotope beam characterization (via nuclear spectroscopy) at the ISAC yield station, the simulation data is a pivotal foundation for the development of better targets and the production of new and more intense isotope beams. Using simulation and yield results, the average release time of francium from uranium carbide targets was determined, providing a better understanding of the dynamics that govern the extraction of isotopes from the target. Yield and simulation results are accessible in a database, helping researchers to devise and plan experiments.